![]() ![]() Unpack them using the commandsĬ Ĭ Ĭ Ĭ Results provide strong support for similar ongoing efforts to produceĬreate a working directory into which you will download the data.ĭownload the MAGIC genotypes, formatted for the HAPPY package analysis, into the analysis directory. Mapping population by mapping several known QTL with high precisionĪnd by finding novel QTL for germination data and bolting time. Show how the power to detect a QTL and the mapping accuracy vary,ĭepending on QTL location. Lines were doubled the mapping error would be under 200 kb. Phenotypic variance will be detected in most situations with anĪverage mapping error of about 300 kb, and that if the number of We show by simulation that QTL explaining 10% of the Reconstructing the genome of each line as a mosaic of theįounders. Analytical methods were developed toįine-map quantitative trait loci (QTL) in the MAGIC lines by With 1,260 single nucleotide polymorphisms and phenotyped forĭevelopment-related traits. These lines and the 19 founders were genotyped Here, we present the first panel of MAGIC linesĭeveloped: a set of 527 recombinant inbred lines (RILs) descendedįrom a heterogeneous stock of 19 intermated accessions of the plantĪrabidopsis thaliana. Precision with which QTL can be mapped, improving the outlook for One such alternative, the Multiparent Advanced Generation Limitations, therefore alternative resources for the geneticĭissection of complex traits continue to be sought. Have employed either simple synthetic populations with restrictedĪllelic variation or performed association mapping on a sample of Variation remains a fundamental problem in genetics. Natural allelic variation that underlies quantitative trait ![]() See also a different way of analysing these data, based on.The data and resources for MAGIC nowīeen expanded to 703 genotyped lines and the SNPs remapped to TAIR9/TAIR10. Note that the original 2009 paper used only 527 MAGIC lines and.Purugganan, Caroline Durrant, Richard Mott PLoS Kover, William Valdar, Joseph Trakalo, Nora Scarcelli, Ian M. The MAGIC lines and the genotypes are described inĪ Multiparent Advanced Generation Inter-Cross to Fine-Map Quantitative Traits in Arabidopsis thaliana.Methods and software described here are based around 1200 SNP To map QTLs in the panel of 703 Arabidopsis MAGIC recombinant inbred lines. This document describes in detail how to install and run software.QTL Mapping using MAGIC Arabidopsis Recombinant Inbred Lines ![]()
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